Evidence suggesting that oral corticosteroids increase mortality in stable chronic obstructive pulmonary disease
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چکیده
منابع مشابه
Evidence suggesting that oral corticosteroids increase mortality in stable chronic obstructive pulmonary disease
BACKGROUND Oral corticosteroids were used to control stable chronic obstructive pulmonary disease (COPD) decades ago. However, recent guidelines do not recommend long-term oral corticosteroids (LTOC) use for stable COPD patients, partly because it causes side-effects such as respiratory muscle deterioration and immunosuppression. Nonetheless, the impact of LTOC on life prognosis for stable COPD...
متن کاملCHRONIC OBSTRUCTIVE PULMONARY DISEASE Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease
D D Sin, L Wu, J A Anderson, N R Anthonisen, A S Buist, P S Burge, P M Calverley, J E Connett, B Lindmark, R A Pauwels , D S Postma, J B Soriano, W Szafranski, J Vestbo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کامل[Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease].
BACKGROUND Clinical studies suggest that inhaled corticosteroids reduce exacerbations and improve health status in chronic obstructive pulmonary disease (COPD). However, their effect on mortality is unknown. METHODS A pooled analysis, based on intention to treat, of individual patient data from seven randomised trials (involving 5085 patients) was performed in which the effects of inhaled cor...
متن کاملOral corticosteroids for exacerbations of chronic obstructive pulmonary disease.
Background. The role of oral corticosteroids in treating patients with exacerbations of chronic obstructive pulmonary disease (COPD) remains contentious. We assessed in a prospective, randomised, doubleblind, placebo-controlled trial the effects of oral corticosteroid therapy in patients with exacerbations of COPD requiring hospital admission. Methods. We recruited patients with non-acidotic ex...
متن کاملEvaluation of Prognostic Factors of Mortality in Patients with Chronic Obstructive Pulmonary Disease
Background and Objective: Chronic Obstructive Pulmonary Disease (COPD) is a chronic obstructive and irreversible disease which has a high mortality and morbidity rate. Systemic inflammation and the thrombotic process can influence the prognosis of these patients. The objectives of this study were to evaluate prognostic effects of CBC indices (WBC, PMN, MPV, RDW), forced expiratory volume-one se...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2014
ISSN: 1465-9921
DOI: 10.1186/1465-9921-15-37